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Repligen Corporation 特约代理
Product Introduction
Repligen Corporation 特约代理
品牌名称Repligen Corporation 特约代理
品牌logo
公司网址：
http://www.repligen.com/
Repligen is a bioprocessing-focused life sciences company bringing over 30 years of expertise and innovation to our customers. We are inspiring advances in bioprocessing through the development and commercialization of high-value products and flexible solutions that address critical steps in the production of biologic drugs, principally monoclonal antibodies.
Our core Protein A affinity ligands business is complemented by an expanding suite of technology-leading bioprocessing products that we sell direct to biopharmaceutical companies and contract manufacturers worldwide. All of our bioprocessing products are meaningfully differentiated from alternatives to the benefit of our customers. Our Protein A ligands are used to purify over 50 monoclonal antibody-based drugs on the market and more than 300 in clinical development. Our XCell™ ATF cell concentration device, and cell culture supplements are at the forefront of innovation in bioprocessing. To provide customers with the broadest selection of pre-packed chromatography columns from bench-scale to production-scale, Repligen acquired Atoll GmBH of Weingarten, Germany, solidifying Repligen as a leading supplier in this fast-growing segment.
Our core Protein A affinity ligands business is complemented by an expanding suite of technology-leading bioprocessing products that we sell direct to biopharmaceutical companies and contract manufacturers worldwide. All of our bioprocessing products are meaningfully differentiated from alternatives to the benefit of our customers. Our Protein A ligands are used to purify over 50 monoclonal antibody-based drugs on the market and more than 300 in clinical development. Our XCell™ ATF cell concentration device, and cell culture supplements are at the forefront of innovation in bioprocessing. To provide customers with the broadest selection of pre-packed chromatography columns from bench-scale to production-scale, Repligen acquired Atoll GmBH of Weingarten, Germany, solidifying Repligen as a leading supplier in this fast-growing segment.
产品列表：
XCell™ ATF System - Stainless Steel
XCell™ ATF Cell Retention System
The XCell™ ATF System in stainless steel comes in five different sizes for operation from lab-scale to production-scale. Each system consists of a diaphragm pump in a stainless steel housing, a single-use hollow fiber filter cartridge, and a control system.
•XCell™ ATF 2 System
•XCell™ ATF 4 System
•XCell™ ATF 6 System
•XCell™ ATF 8 System
•XCell™ ATF 10 System
XCell™ ATF System - Stainless Steel
Technology
The XCell™ ATF System is based on award-winning Alternating Tangential Flow (XCell™ ATF) technology, created by the action of a diaphragm moving upward and downward within a pump head, connected to a filter housing and attached to a bioreactor. Alternating tangential flow is attained by the action of a diaphragm pump.
XCell™ atf technology
Benefits
ATF Cell Retention System
•Continuous, provides clarified harvest ready for capture chromatography
•Efficient, delivers 100% cell retention, increases productivity
•Intensified, generates high cell concentration and viability
•Flexible, connects to any bioreactor and can be used in a variety of applications
•Gentle, reduces cell stress, increases cell viability and productivity
•Easy to use, reduces setup time and user training
•Scalable, adapts from development-scale to production-scale
•Self-cleaning, reduces biofilm build up on the hollow fiber filter
Applications
ATF Cell Retention System
Perfusion
Perfusion, or upstream continuous processing, has been used since the 1980s. High cell density perfusion, or ATF perfusion, delivers higher cell concentration and cell viability.
N-1 Perfusion
N-1 perfusion refers to the intensification of cell growth in the step prior to the production bioreactor (N). This process intensification is done using perfusion in the N-1 bioreactor for high cell density seeding of the production bioreactor (N), or removal of the N-1 bioreactor if the N-2 bioreactor can provide enough cells for the production bioreactor (N).
High Density (HD) Cell Banking
High density (HD) cell banking is a novel method for seed train optimization using perfusion to intensify cell density and reduce the number of early-stage expansion steps.
Learn more
Connecting to a bioreactor
The XCell™ ATF System is easy to connect to standard bioreactors, including
•Glass bioreactors (1L - 20L)
•Wave type single-use bioreactor (1L - 1000L)
•Stirred tank single-use bioreactor (2L - 2000L)
•Stainless steel bioreactors (20L - 2000L)
A complete guide includes the range of standard adaptors and ports that fit all bioreactor equipment.
SEE GUIDE
Resources
LONG®R3 IGF-I Cell Culture Supplement
LONG® EGF Cell Culture Supplement
Alternating Tangential Flow (XCell™ ATF) technology
XCell™ ATF Cell Retention System
The XCell™ ATF System integrates a diaphragm pump, a stainless steel housing, and a single-use hollow fiber filter cartridge.
•Connect the XCell™ ATF System to a bioreactor.
•Pressurized air flows into the bottom of the ATF pump.
•The air pressure forces the diaphragm gently up, displacing liquid and creating a fast flow of cell culture media across the surface of the hollow fiber filter.
•There is rapid flow of media through the filter fibers, with a cell-free filtrate being generated.
•The cell culture fluid remaining on the upstream side of the hollow fiber filter is returned back into the bioreactor.
•The system then reverses: air is exhausted through the pump bottom.
•The diaphragm moves down creating a rapid flow of cell culture media from the bioreactor back into the XCell™ ATF System. The system is now ready for the next cycle.
•The cycle repeats approximately every 5 seconds.
SEE MOVIE
Unique design features
High flow with low shear
The gentle action of the diaphragm in an XCell™ ATF System minimizes shear during pump operation. This results in separation of cells, cleaning of the filter surface and delivers extremely high cell concentrations such as 100-200x106 cells/ml in many different cell line types including CHO.
Reduced filter fouling
The combination of a single bioreactor connection and reversible flow through the filter with alternating high and low pressure cycles results not only in efficient tangential flow but also in significant trans-membrane fluxes with back-flushing action on each cycle.
Hollow fiber filter technology
XCell™ ATF hollow fiber filter
In XCell™ ATF, the alternating tangential flow sweeps the membrane surface, but in addition, a backflush occurs with each cycle because the XCell™ ATF reverses flow within the same line. This action cleans the filter while minimizing gel layer formation and ultimately reducing fouling.
Scale-up parameters
我们的产品
抗体类：
一抗／二抗产品
标记一抗／二抗相关产品
Elisa试剂盒、配对抗体
多种试剂盒、PCR试剂盒、DNA提取试剂盒、RT实时定量试剂盒
蛋白类：
重组蛋白／天然构象蛋白
小分子抗原、细胞因子
多肽类：
化妆品肽
Fmoc-氨基酸
Boc-氨基酸
Z-氨基酸
短肽试剂
分子细胞类：
肿瘤细胞／传代细胞／原代细胞
定制化的耐药细胞
高品质血清
常用培养基，分子细胞实验试剂
合成引物／载体／质粒
化学品与试剂：
化学中间体
化学合成常用试剂
定制中间体合成
对照品／标准品
液相／气相色谱实验佐剂
优势产品：
ATGen, Beckman Coulter, InvivoGen, Meridian Life Science, National Institute for Biological Standards and Control, Protein Specialists, Roboz Surgical Instrument, 2A PharmaChem USA, Abbexa, Abnova, Accurate chemical, Addgene, Advanced Instruments, AFFINITY BIOLOGICALS, Affymetrix (eBioscience), AG Scientific, Agilent, Agrisera, AK Scientific, Akina, Alfa Aesar, Allele biotech, Alomone Labs, Alpco (American Laboratory Products Company), Alpha Diagnostics Intl, Altogen Biosystems, Ambergen, Ambion (Thermo), American Peptide, AMRESCO, ANIARA, Anogen, Antibodies Corporated (Neuromab), ApexBio, Arista Biologicals, ARMI (IRMM), AROTEC, Ascendance Biotechnology, ATCC, Avantilipids, Avidity, Aviscera Bioscience, Bachem Americas, BBI Solutions, BD Sciences, Beckman Coulter, Berry & Associates, Bethyl Laboratories, BioAssay Systems, Bioclone, Biocytex, BioFire Defense, Biogenex, Biolegend, Biolog (Axxora), Biomedical Technologies, Biomol, Biopal, Bio-rad, Biosettia, Biotium, Boston Biochem, R&D, BPS Bioscience, Calbiotech, Adipogen, Carbosynth, cDNA Resource Center, Cell Biolabs, Cell Technology, Cellbio, CELLSCRIPT, Cellular Dynamics International, Celprogen, Cen-Med Enterprises, Charles River Microbial Solutions, Chiralix B.V., CHROMOGENIX (DiaPharma Group), CHRONO-LOG Corporation, Click Chemistry Tools, Clontech, Cloud-Clone Corp, Complement tech, Creative Bioarry, Creative Biolabs, Creative BioMart, Creative PEGWorks, CST, Cusabio, Dako North America, Detroit R&D, Dextra, DHI, Diagnostic Automation/Cortez Diagnostics, Rapidtest, Diarect, DiscoveRx Corporation, DRG International, DSHB, E&K Scientific, Eagle Bio, eBioscience, Echelon, Edge BioSystems, eEnzyme, ELASTIN PRODUCTS COMPANY, Electron Microscopy Sciences (Dumonttweezers), EMD Millipore Corporation, EMMX Biotechnology, Empire Genomics, ELECTRON MICROSCOPY SCIENCES, Encapsula NanoSciences (Clodrosome), Enzo Life Sciences, Enzyme Research Laboratories, Epicentre, Epitope Diagnostics, Equitech Bio, Exalpha biological, Exiqon, Fine Science Tools, Fisher Scientific, Fitzgerald, Flow Tech, GATTAquant GMBH, GE Healthcare Life Sciences, GeneMark, GeneTex, Genovis, GenWay Biotech, GEORGE KING Bio-MEDICAL, Gibco, Glycotech, GM Biosciences, Green Mountain Antibodies (GMA), GroPep Bioreagents Pty, HistoBioTec, Hitobiotec Corp, HTI (Haematologic Technologies), IBI Scientific, Illumina, Immunodiagnostic Systems, Indoor Biotechnologies, Innovative Research, Instrumentation Laboratory (WERFEN USA), Invitrogen, Thermo Fisher, Invivogen, Irvine Scientific, Jackson Immunoresearch Laboratories, Jenkemusa, Kalen Biomedical, KAMIYA BIOMEDICAL COMPANY, KENOSHA c.v, KeraFAST, Kingfisher Biotech, Krackeler Scientific, LDN, Rocky Mountain Diagnostics, Leinco, LI-COR Biosciences, LifeSpan, List Biological Labs, Macryocyclics, Matreya, Mayflower Bioscience, MBL International Corporation, Mercodia, Meridian Life Science, Micropoint Bioscience., Milenia Biotec, MO BIO Laboratories, Mobitech (Boca Scientific), Molecular Innovations, Moravek Biochemicals, MP Biomedicals, Nanostructured & Amorphous Materials, National Diagnostics, NCIMB (Microbiologics), NEB, Neoscientific, Neuro Probe, NIST, NovaMatrix, Novozymes, Novusbio, Omicron Biochemicals, OncoImmunin., Optocell, PartsSource (Beckman), PBL Assay Science, Phoenix Pharmaceuticals, Phoenixpeptide, PhosphoSolutions, PLI (Peninsula Laboratories International), Polymer Source, Polymun Scientific, Polyplus (vwr), Premetek, Progen Biotech, ProSpec, QIAGEN, Quidel, R&D systems, Tocris, RayBiotech, Repligen Corporation, Roboz Surgical Instrument, rPeptide, rpicorp, RTI, Salimetrics, Sartorius Stedim North America, Scripps Laboratories, Seven Hills Bioreagents, Sigma-Aldrich, SignalChem, Solarbio, Spring bioscience, Steraloids, Sterlitech Corporation, Stratagene (Agilent), Streck, Sunrise Science Products, Swant, Symansis, System Biosciences (SBI), Takara, The Adipogen, The McCrone Group, ThermoFisher, Thomas Scientific, TLC Pharmaceutical Standards, Transgenomic, Trevigen, TriLink BioTechnologies, Twistdx, TwistDX Limited, UNC, UPENN, USBiological, USP (The United States Pharmacopeial Convention), Valasciences, Valley Biomedical Products & Services, Vanderbilt, Vector Laboratories, Virogen, Viva Bioscience, vwr, WSU Monoclonal Antibody Center, Xona Microfluidics, ZEDIRA GmbH, ZeptoMetrix Corporation, ZYAGENE
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1、覆盖全球采购中心。采购中心总部位于美国俄亥俄州，拥有30多人的采购团队，采购产品涉及抗体、蛋白、细胞、血清、耗材等全门类生物产品。
2、货品种类丰富。目前，我公司以美国品牌为主体，不断与其他欧美200多个品牌建立了正式的代理及其他合作关系。货品涵盖众多的生物试剂门类！
3、货期反应迅速。我公司发货反应速度及时，与国内一流的物流公司有着长期的合作关系。一般2-3周即可到货，超过时限加急费全免！
4、价格优惠合理。公司依托全球一体化的整合优势，可以为您提供一个有竞争力的价格！
5、口碑好、信誉高。竭诚、热诚的服务，使得我公司的客户群体不断扩大。我们的客户群包括中国科学院、清华大学、北京大学、复旦大学、南京大学众多高校。众多医药公司也选择成为我们的忠诚合作伙伴：礼来制药、罗氏上海研发中心、美迪西医药、保诺生物、药明康德等500多家公司！
我们致力于发展为我国重要的生命科学试剂和成果转化一体化的领导者，致力于成为中国最大的科研试剂产品供应商之一。
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| 销售部 | 顾先生 | 1916510334@qq.com | 18321282235 | 1916510334 | |
| 技术部 | 技术支持 | 1781364813@qq.com | 13816899465 | 1781364813 |
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