Alternative Names:

EBI; F box like/WD repeat protein TBL1X; F-box-like/WD repeat-containing protein TBL1X; SMAP55; TBL1; TBL1X;

Application:

WB ICC/IF

Reactivity:

Human

Dilution:

WB 1:1000 ICC/IF 1:100

	Western blot detection of TBL1X in SW480 cell lysates using TBL1X mouse mAb (1:1000 diluted).Predicted band size:58KDa.Observed band size:58KDa.
	Immunofluorescent analysis of HeLa cells fixed with 4% Paraformaldehyde and using anti-TBL1X mouse mAb (dilution 1:100).

Purification:

Affinity-chromatography

Specificity:

TBL1 Mouse mAb detects endogenous levels of total TBL1

Immunogen:

Purified recombinant human TBL1 protein fragments expressed in E.coli.

Description:

Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.