Alternative Names:

DAP-150; DP-150; HMN7B; P135;

Application:

WB IP

Reactivity:

Human

Dilution:

WB 1:500 IP

	Western blot detection of Dynactin 1 in K562,MCF7,293T and Hela cell lysates using Dynactin 1 mouse mAb (1:500 diluted).Predicted band size:150KDa.Observed band size: 150KDa.
	Immunoprecipitation analysis of Hela cell lysates using Dynactin 1 mouse mAb.

Purification:

Affinity-chromatography

Specificity:

Dynactin 1(N-term) Mouse mAb detects endogenous levels of total Dynactin 1(N-term)

Immunogen:

Purified recombinant Dynactin 1 protein fragments expressed in E.coli

Description:

Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein-dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles.

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.