Alternative Names:

CIMT1; GLM1; NR1C3; Nuclear receptor subfamily 1 group C member 3; Peroxisome Proliferator Activated Receptor gamma; PPAR gamma; PARG; PPARG1; PPARG2;

Application:

WB

Reactivity:

Transfected

Dilution:

WB 1:500

	Western blot detection of PPARγ fragment in CHO-K1 cell lysate (A) and CHO-K1 transfected by pEGFP-C1-PPARγ (B) cell lysate using HER2/ErbB2 mouse mAb (1:500 diluted).Predicted band size: 53kDa.Observed band size:53kDa.

Purification:

Affinity-chromatography

Specificity:

PPARγ Mouse mAb detects endogenous levels of total PPARγ

Immunogen:

Purified recombinant human PPARγprotein fragments expressed in E.coli.

Description:

Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids.

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.