Alternative Names:

BB2; CD54; P3.58; MyD10; ICAM1;

Application:

WB

Reactivity:

Human

Dilution:

WB 1:1000

	Western blot detection of CD54(ICAM-1) in Raji and SW480 cell lysates and using CD54(ICAM-1) mouse mAb (1:1000 diluted).Predicted band size: 58KDa.Observed band size: 96KDa.

Purification:

Affinity-chromatography

Specificity:

CD54(ICAM-1) Mouse mAb detects endogenous levels of total CD54(ICAM-1)

Immunogen:

Purified recombinant human CD54(ICAM-1) protein fragments expressed in E.coli.

Description:

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.