Alternative Names:

CD61; GP3A; GPIIIa; Integrin beta-3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITB3; ITGB3;

Application:

WB

Reactivity:

Human

Dilution:

WB 1:1000

	Western blot detection of Integrin beta 3(N-terminus) in 15ug and 25ug Leukocyte whole cell lysate using Integrin beta 3(N-terminus) mouse mAb (1:1000 diluted).Predicted band size:110KDa.Observed band size:110KDa.

Purification:

Affinity-chromatography

Specificity:

Integrin β 3(N-term) Mouse mAb detects endogenous levels of total Integrin β 3(N-term)

Immunogen:

Purified recombinant human Integrin beta 3(N-terminus) protein fragments expressed in E.coli.

Description:

Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin.

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.