Alternative Names:

FKHR; FOXO1; FOXO1A; Forkhead box protein O1A; Forkhead in rhabdomyosarcoma;

Application:

WB

Reactivity:

Human

Dilution:

WB 1:1000

	Western blot detection of FOXO1(C-terminus) in A431 and Hela cell lysates using FOXO1(C-terminus) mouse mAb (1:1000 diluted).Predicted band size:70KDa.Observed band size: 70KDa.

Purification:

Affinity-chromatography

Specificity:

FOXO1(C-term) Mouse mAb detects endogenous levels of total FOXO1(C-term)

Immunogen:

Purified recombinant human FOXO1(C-terminus) protein fragments expressed in E.coli.

Description:

Transcription factor which acts as a regulator of cell responses to oxidative stress. In the presence of KIRT1, mediates down-regulation of cyclin D1 and up-regulation of CDKN1B levels which are required for cell transition from proliferative growth to quiescence (By similarity)

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.