Alternative Names:

RAD51 homolog A; DNA repair protein RAD51 homolog 1; RAD51A; RECAhomolog S. cerevisiae; RAD51A; RECA; Rad 51; RecA homolog E. coli; RecA like protein;

Application:

WB

Reactivity:

Human,Mouse,Rat,Monkey

Dilution:

WB 1:1000

	Western blot detection of Rad51 in CHO-K1,COS7,C6,3T3 and Hela cell lysates using Rad51 mouse mAb (1:1000 diluted).Predicted band size:37KDa.Observed band size:37KDa.

Purification:

Affinity-chromatography

Specificity:

Rad51 Mouse mAb detects endogenous levels of total Rad51

Immunogen:

Recombinant protein of human Rad51.

Description:

Participates in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.