Alternative Names:

ASH; Grb3-3; MST084; NCKAP2; MSTP084; EGFRBP-GRB2;

Application:

WB

Reactivity:

Human,Mouse,Rat

Dilution:

WB 1:1000

	Western blot detection of GRB2 in K562,Raji,Jurkat,Ramos,C6,3T3 and Hela cell lysates using GRB2 mouse mAb (1:1000 diluted).Predicted band size:25KDa.Observed band size:25KDa.

Purification:

Affinity-chromatography

Specificity:

GRB2 Mouse mAb detects endogenous levels of total GRB2

Immunogen:

Recombinant protein of human GRB2.

Description:

Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Isoform GRB3-3 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element.

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.