Alternative Names:

AH119; AP-1; AP1; Activator protein 1; Jun A; Proto-oncogene c-jun; RJG-9; V-jun avian sarcoma virus 17 oncogene homolog; c-Jun; p39;

Application:

WB

Reactivity:

Dilution:

WB 1:1000

	Western blot detection of c-JUN in CHO-K1 transfected by PEGFP-C1-c-JUN（A）and CHO-K1 cell lysate（B）cell lysate using c-JUN mouse mAb (1:1000 diluted).Predicted band size:43/48KDa.Observed band size:43/48KDa.

Purification:

Affinity-chromatography

Specificity:

c-JUN Mouse mAb detects endogenous levels of total c-JUN

Immunogen:

Purified recombinant human c-JUN protein fragments expressed in E.coli.

Description:

Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.