Alternative Names:

FLAP1; GC binding factor 2; GCF2; HUFI1; LRRFIP 1; Lrrfip1; NEDD8 conjugating enzyme; TRIP;

Application:

WB

Reactivity:

Human,Mouse

Dilution:

WB 1:1000

	Western blot detection of LRRFIP1 in Raji,C2C12,MCF7 and Jurkat cell lysates using LRRFIP1 mouse mAb (1:1000 diluted).Predicted band size:89KDa.Observed band size:160KDa.

Purification:

Affinity-chromatography

Specificity:

LRRFIP1 Mouse mAb detects endogenous levels of total LRRFIP1

Immunogen:

Purified recombinant human LRRFIP1 protein fragments expressed in E.coli.

Description:

Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression.

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.