Alternative Names:

RNA-binding protein Musashi homolog 1; Musashi-1; MSI1;

Application:

WB

Reactivity:

Human,Mouse,Rat

Dilution:

WB 1:1000

	Western blot detection of Musashi-1 in U87MG,C6,IMR32,mouse brain and PC12 cell lysates and using Musashi-1 mouse mAb (1:1000 diluted).Predicted band size: 39KDa.Observed band size:39KDa.

Purification:

Affinity-chromatography

Specificity:

Musashi-1 Mouse mAb detects endogenous levels of total Musashi-1

Immunogen:

Purified recombinant human Musashi-1 protein fragments expressed in E.coli.

Description:

RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U1-3AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.