Alternative Names:

HSPC321; SWA 70 protein;SWAP 70; SWAP switching B-cell complex 70kDa subunit; SWAP70; Switch associated protein 70;

Application:

WB IP

Reactivity:

Human,Mouse,Rat,Monkey

Dilution:

WB 1:1000 IP

	Western blot detection of SWAP70 in COS7,293T,C6,3T3 and Hela cell lysates and using SWAP70 mouse mAb (1:1000 diluted).Predicted band size: 70KDa.Observed band size: 70KDa.
	Immunoprecipitation analysis of Hela cell lysate using SWAP70 mouse mAb.

Purification:

Affinity-chromatography

Specificity:

SWAP70 Mouse mAb detects endogenous levels of total SWAP70

Immunogen:

Purified recombinant human SWAP70 protein fragments expressed in E.coli.

Description:

Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling.

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.