Alternative Names:

CBR; hCBR1; SDR21C1;

Application:

WB ICC/IF

Reactivity:

Human

Dilution:

WB 1:1000 ICC/IF 1:100

	Western blot detection of CBR1 in Hela,A431 and MDA-MB-468 cell lysates using CBR1 mouse mAb (1:1000 diluted).Predicted band size:30KDa,Observed band size:30KDa.
	Immunofluorescent analysis stain of Hela using CBR1 mouse mAb (1:100).

Purification:

Affinity-chromatography

Specificity:

CBR1 Mouse mAb detects endogenous levels of total CBR1

Immunogen:

Purified recombinant human CBR1 protein fragments expressed in E.coli

Description:

NADPH-dependent reductase with broad substrate specificity.Catalyzes the reduction of a wide variety of carbonyl compounds including quinones,prostaglandins, menadione,plus various xenobiotics.Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol.

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.