Alternative Names:

Edr; HB-1; Mar2; MEF3L; Mart2; RGAG3; KIAA1051

Application:

WB IP

Reactivity:

Human

Dilution:

WB 1:1000 IP

	Western blot detection of PEG10 in Hela cell lysates using PEG10 mouse mAb (1:1000 diluted).Predicted band size:55KDa.Observed band size:55KDa,95KDa.
	Immunoprecipitation analysis of Hela cell lysates using PEG10 mouse mAb.

Purification:

Affinity-chromatography

Specificity:

PEG10 Mouse mAb detects endogenous levels of total PEG10

Immunogen:

Purified recombinant human PEG10 protein fragments expressed in E.coli.

Description:

Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.