Alternative Names:

Protein lin-28 homolog A; Zinc finger CCHC domain-containing protein 1; LIN28A; CSDD1; LIN28; ZCCHC1;

Application:

WB

Reactivity:

Human,Mouse

Dilution:

WB 1:1000

	Western blot detection of LIN28 in NTERA and F9 cell lysates using LIN28A mouse mAb (1:1000 diluted).Predicted band size:26KDa.Observed band size:26KDa.

Purification:

Affinity-chromatography

Specificity:

LIN28A Mouse mAb detects endogenous levels of total LIN28A

Immunogen:

Purified recombinant human LIN28A protein fragments expressed in E.coli

Description:

Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis.Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and,indirectly,in stabilizing the mRNAs.Binds IGF2 mRNA,MYOD1 mRNA,ARBP/36B4 ribosomal protein mRNA and its own mRNA.

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.