Alternative Names:

NOG; Noggin; SYM1; Symphalangism 1 (proximal); SYNS1.

Application:

WB ICC/IF

Reactivity:

Dilution:

WB 1:1000 ICC/IF 1:100

	Western blot detection of Noggin in CHO-K1 cell lysates over-expressing Noggin-PDGFR transmembrane domain fused protein using Noggin mouse mAb (1:1000 diluted).Predicted band size:26KDa.Observed band size:37KDa.
	Immunofluorescent analysis of HeLa cells surface-expressing Noggin-PDGFR transmembrane domain fused protein using Noggin mouse mAb (dilution 1:100).

Purification:

Affinity-chromatography

Specificity:

Noggin Mouse mAb detects endogenous levels of total Noggin

Immunogen:

Purified recombinant human Noggin protein fragments expressed in E.coli.

Description:

Essential for cartilage morphogenesis and joint formation.Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.