Alternative Names:

Apoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4

Application:

WB

Reactivity:

Human,Monkey

Dilution:

WB 1:1000

	Western blot detection of Bax in COS7,Raji,CEM and Hela cell lysates using Bax mouse mAb (1:1000 diluted). Predicted band size:20KDa. Observed band size:20KDa.

Purification:

Affinity-chromatography

Specificity:

Bax Mouse mAb detects endogenous levels of total Bax

Immunogen:

Purified recombinant human Bax protein fragments expressed in E.coli

Description:

Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis.

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.