Alternative Names:

APRF;Acute-phase response factor; Stat3;

Application:

WB

Reactivity:

Human,Mouse,Rat,Monkey,Hamster

Dilution:

WB 1:1000

	Western blot detection of STAT3 in CHO-K1,C6,3T3,K562,CEM,Jurkat,Hela,MCF7,COS7,293T,A431 and A549 cell lysates using STAT3 mouse mAb (1:1000 diluted).Predicted band size:88KDa.Observed band size:88KDa.

Purification:

Affinity-chromatography

Specificity:

STAT3 Mouse mAb detects endogenous levels of total STAT3

Immunogen:

Purified recombinant human STAT3 protein fragments expressed in E.coli

Description:

Signal transducer and transcription activator that mediates cellular responses to interleukins,KITLG/SCF and other growth factors.May mediate cellular responses to activated FGFR1,FGFR2,FGFR3 and FGFR4.Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes.

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.