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Details
Alternative Names:
Transcription factor ISGF-3 components p91/p84;ISGF3; CANDF7; STAT 1; Stat1;
Application:
WB IP
Reactivity:
Human,Monkey
Dilution:
WB 1:1000 IP
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Western blot detection of STAT1 in Hela,MCF7,COS7,SW480 and A549 cell lysates using STAT1 mouse mAb (1:1000 diluted).Predicted band size:91KDa.Observed band size:91KDa. |
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Immunoprecipitation analysis of Hela cell lysates using STAT1 mouse mAb. |
Purification:
Affinity-chromatography
Specificity:
STAT1 Mouse mAb detects endogenous levels of total STAT1
Immunogen:
Purified recombinant human STAT1 protein fragments expressed in E.coli
Description:
Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs),cytokine KITLG/SCF and other cytokines and other growth factors.Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors,signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2.
Storage Condition and Buffer:
Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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