Alternative Names:

Bag 1;BAG1;BAG1S;HAP;BAG1M;BAG1L specific;RAP46;

Application:

WB

Reactivity:

Dilution:

WB 1:1000

	Western blot analysis of extracts from CHO-K1 cells, transfected with a human pEGFP-C1-BAG1 construct (A) or transfected with a human pEGFP-C1 construct (B), using Bag1 mouse mAb (1:1000 diluted).

Purification:

Affinity-chromatography

Specificity:

Bag1 Mouse mAb detects endogenous levels of total Bag1

Immunogen:

Purified recombinant human Bag1 protein fragments expressed in E.coli.

Description:

Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.Inhibits the pro-apoptotic function of PPP1R15A,and has anti-apoptotic activity.Markedly increases the anti-cell death function of BCL2 induced by various stimuli.