Alternative Names:

ck8; cyk8; Cytokeratin endo A; Cytokeratin8; DreK8; Keratin8; Krt8; CK18; CYK18; Cytokeratin 18; K18; Keratin 18; Keratin D;

Application:

WB ICC/IF

Reactivity:

Human

Dilution:

WB 1:1000 ICC/IF 1:200

	Western blot detection of keratin8/18 in Hela, A549, PC-3 and SKOV3 cell lysates using keratin8/18 antibody (1:1000 diluted).Predicted band size:55KDa.Observed band size:55KDa.
	Immunofluorescent analysis of HeLa cells using anti-keratin8/18 antibody (dilution 1:200).

Purification:

Affinity-chromatography

Specificity:

Keratin8/18 Mouse mAb detects endogenous levels of total Keratin8/18

Immunogen:

Recombinant protein corresponding to full length Keratin8 of human.

Description:

Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle./Involved in the uptake of thrombin-antithrombin complexes by hepatic cells By similarity. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane.

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.