Alternative Names:

Apoptosis regulator Bcl-2; BCL2;

Application:

WB

Reactivity:

Human

Dilution:

WB 1:500

	Western blot detection of BCL2 in Jurkat and THP-1 cell lysates using BCL2 antibody (1:500 diluted).Predicted band size:29KDa.Observed band size:26KDa.

Purification:

Affinity-chromatography

Specificity:

Bcl-2 Mouse mAb detects endogenous levels of total Bcl-2

Immunogen:

Recombinant protein corresponding to fragment (aa/1-195) BCL2.

Description:

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases.

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.