Alternative Names:

MAPK3; MK03; MNK1; p44-ERK1; P44-ER; ERK-1; ERK1; ERT2; kinase ERK1; MAP kinase 1; MAPK 1

Application:

WB

Reactivity:

Human,Mouse,Rat

Dilution:

WB 1:1000

	Western blot analysis of extracts from PC12,C6,mouse Brain,3T3,K562,Jurkat and Hela cell lysates using p44/42 MAPK (Erk1/2) mouse mAb (1:1000 diluted).Predicted band size:42/44KDa.Observed band size:42/44KDa.

Purification:

Affinity-chromatography

Specificity:

p44/42 MAPK (Erk1/2) Mouse mAb detects endogenous levels of total p44/42 MAPK (Erk1/2)

Immunogen:

Human p44 MAPK (Erk1) synthetic peptide conjugated to KLH.

Description:

Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2).

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.