Alternative Names:

SEK; HEK8; TYRO1;

Application:

ELISA WB

Reactivity:

Human

Dilution:

ELISA 1/10000 WB 1/500 - 1/2000

	Western blot analysis using EphA3 mouse mAb against truncated Trx-EphA3 recombinant protein (1) and truncated EphA3(aa566-983)-hIgGFc transfected CHO-K1 cell lysate(2).

Purification:

Affinity-chromatography

Specificity:

EphA3 antibody detects endogenous levels of total EphA3

Immunogen:

Recombinant human EphA3 protein.

Description:

EphA3: EPH receptor A3. This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene.

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.