Alternative Names:

hp51CN; Inositol polyphosphate-5-phosphatase of 145 kDa; inositol polyphosphate-5-phosphatase, 145kDa; INPP5D; MGC104855; MGC142140; MGC142142; p150Ship; Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1; SH2 containing inositol phosphatase, isofor

Application:

WB

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500~1:3000

	Western blot analysis on HepG2 cell lysate using SHIP1 Antibody

Purification:

Affinity-chromatography

Specificity:

SHIP1 antibody detects endogenous levels of total SHIP1

Immunogen:

A synthesized peptide derived from human SHIP1

Description:

SHIP an SH2-containing inositol phosphatase. A hemopoietic-specific phosphatase that regulates cell survival, growth, cell cycle arrest and apoptosis. Hydrolyzes Ins(1,3,4,5)P4 and PtdIns(3,4,5)P3. A cytosolic protein with a SH2 domain in its N-terminus and two NPXY Shc binding motifs at its C-terminus.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.