Alternative Names:

ABAD; CAMR; HCD2; MHBD; HADH2

Application:

WB

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500-1:1000

	Western blot analysis of extract from JK, HUVEC, HepG2 and Hela cells using ERAB Antibody

Purification:

Affinity-chromatography

Specificity:

The antibody detects endogenous level of total ERAB protein.

Immunogen:

Peptide sequence around aa.253~257(L-D-G-A-I)derived from Human ERAB.

Description:

Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.