Alternative Names:

ARC205, Activator-recruited cofactor 205 kDa component, DRIP205, PBP, PPAR-binding protein, PPRB, Peroxisome proliferator-activated receptor binding protein, TRIP2, Thyroid hormone receptor associated protein 220, Thyroid hormone receptor-associated prote

Application:

WB IF/ICC

Reactivity:

Human, Mouse

Dilution:

WB 1:500-1:2000 IF/ICC 1:100-1:500

	Western blot analysis of PPAR-BP expression in HuvEc whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

Purification:

Affinity-chromatography

Specificity:

PPAR-BP Antibody detects endogenous levels of total PPAR-BP

Immunogen:

A synthesized peptide derived from human PPAR-BP

Description:

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.