Alternative Names:

Protein kinase, Ser/Thr (non-receptor), CAMK group, CAMKL family, LKB subfamily

Application:

WB

Reactivity:

Human, Mouse

Dilution:

WB 1:500-1:2000

	Western blot analysis of LKB1 expression in Serum treated HeLa whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

Purification:

Affinity-chromatography

Specificity:

LKB1 Antibody detects endogenous levels of total LKB1

Immunogen:

A synthesized peptide derived from human LKB1

Description:

ubiquitously expressed kinase of the CAMKL family with a tumor suppressor activity. Phosphorylates AGS3 (activator of G-protein signaling 3) GPR domains, regulating the interaction of GPR-containing proteins with G-proteins. Strongest expression in testis and fetal liver. Mutations in LKB1 lead to the Peutz-Jeghers cancer syndrome.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.