Alternative Names:

CD3ε; FLJ18683; T3E; TCRE;

Application:

IHC ICC/IF IP

Reactivity:

Human

Dilution:

IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

	Immunohistochemical analysis of paraffin-embedded mouse spleen, using CD3 epsilon Antibody.

Purification:

Affinity-chromatography

Specificity:

CD3 epsilon Antibody detects endogenous levels of total CD3 epsilon

Immunogen:

A synthesized peptide derived from human CD3 epsilon

Description:

The CD3 complex mediates signal transduction. When T cells encounter antigens via the T cell receptor (TCR), information about the quantity and quality of antigens is relayed to the intracellular signal transduction machinery . This activation process depends mainly on CD3 (Cluster of Differentiation 3), a multiunit protein complex that directly associates with the TCR. CD3 is composed of four polypeptides: ζ, γ, ε and δ.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.