Alternative Names:

APRF;Acute-phase response factor;Signal transducer and activator of transcription 3;Stat3;

Application:

WB IHC ICC/IF IP

Reactivity:

Human Rat

Dilution:

WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

	Western blot analysis of Phospho-STAT3 (S727) expression in A431 cell lysate treated with EGF.
	Immunohistochemical analysis of paraffin-embedded rat brain, using Phospho-STAT3 (S727) Antibody.
	Immunofluorescent analysis of A431 cells treated with EGF, using Phospho-STAT3 (S727) Antibody .

Purification:

Affinity-chromatography

Specificity:

Phospho-STAT3 (S727) Antibody detects endogenous levels of total Phospho-STAT3 (S727)

Immunogen:

A synthesized peptide derived from human Phospho-STAT3 (S727)

Description:

Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.