Alternative Names:

CD22; BLCAM ; Leu14; Lyb8; SIGLEC2 ; B cell receptor CD22 precursor; MGC130020;

Application:

WB

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000

	Western blot analysis of Raji cell lysate using CD22 antibody.

Purification:

Affinity-chromatography

Specificity:

CD22 Antibody detects endogenous levels of total CD22

Immunogen:

A synthesized peptide derived from human CD22

Description:

Acts as a regulator of B cell signaling. CD22 is expressed as both a cytoplasmic and membrane protein during discrete stages of B cell lymphocyte differentiation. The cytoplasmic form of CD22, expressed early in B cell development, is a useful marker for acute lymphocytic leukemia. The membrane form of CD22 is expressed in mature B cells prior to their differentiation into plasma cells. Alternative splicing results in two different isoforms, CD22α and CD22β.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.