Alternative Names:

ADRB2; Alpha-PAK; CDC42/RAC effector kinase PAK-A; EC 2.7.11.1; P65-PAK; P68-PAK; PAK1 (phospho S144); PAK2 (phospho S141); PAK3 (phospho S139);

Application:

WB IHC ICC/IF IP FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:1000~1:10000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50

	Western blot analysis of Phospho-PAK1/2/3 expression in HeLa Cell lysate treated with lambda phosphatase.
	Immunohistochemical analysis of paraffin-embedded mouse brain, using Phospho-PAK1/2/3 (S144+S141+S139) Antibody.

Purification:

Affinity-chromatography

Specificity:

Phospho-PAK1/2/3 (S144+S141+S139) Antibody detects endogenous levels of total Phospho-PAK1/2/3 (S144+S141+S139)

Immunogen:

A synthesized peptide derived from human Phospho-PAK1/2/3 (S144+S141+S139)

Description:

PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.