Alternative Names:

CD51; integrin alpha V; ITAV; MSK8; vitronectin receptor alpha; VNRA; ITGB6;

Application:

WB FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:1000~1:2000 FC 1:20

	Western blot analysis of integrin alpha V expression in A549 cell lysates.

Purification:

Affinity-chromatography

Specificity:

Integrin alpha V Antibody detects endogenous levels of total Integrin alpha V

Immunogen:

A synthesized peptide derived from human Integrin alpha V

Description:

The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.