Alternative Names:

RUNX1; AML1; RUNX2; OSF2; RUNX3; CBFA3;

Application:

WB IHC ICC/IF IP FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

	Western blot analysis of RUNX1/RUNX2/RUNX3 expression in MOLT4 cell lysate.
	Immunohistochemical analysis of paraffin-embedded mouse lung, using RUNX1/RUNX2/RUNX3 Antibody.

Purification:

Affinity-chromatography

Specificity:

RUNX1/RUNX2/RUNX3 Antibody detects endogenous levels of total RUNX1/RUNX2/RUNX3

Immunogen:

A synthesized peptide derived from human RUNX1/RUNX2/RUNX3

Description:

RUNX2 regulates the transcription of various genes including osteopontin, bone sialoprotein, and osteocalcin via binding to the core site of the enhancers or promoters.RUNX3/AML2 is a member of the Runt family of transcription factors. RUNX3 is important for the suppression of cell proliferation in the gastric epithelium, neurogenesis of the dorsal root ganglia, and T cell differentiation.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.