Alternative Names:

SK; DKK-1; Dickkopf-related protein 1; Dickkopf-1; hDkk-1; Dickkopf homolog 1;

Application:

WB IHC ICC/IF FC

Reactivity:

Human Rat

Dilution:

WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50

	Western blot analysis of DKK1 expression in HeLa cell lysate.
	Immunohistochemical analysis of paraffin-embedded human placenta, using DKK1 Antibody.

Purification:

Affinity-chromatography

Specificity:

DKK1 Antibody detects endogenous levels of DKK1

Immunogen:

A synthesized peptide derived from human DKK1

Description:

DKK1: dickkopf homolog 1 (Xenopus laevis), also known as SK. Entrez Protein NP_036374. DKK1 is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.