Alternative Names:

CDCA5; Cell division cycle associated protein 5; Cell division cycle-associated protein 5; p35; Sororin;

Application:

WB IHC ICC/IF FC

Reactivity:

Human

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50

	Western blot analysis of CDCA5 expression in Jurkat cell lysate.
	Immunohistochemical analysis of paraffin-embedded human colon, using CDCA5 Antibody.
	Immunofluorescent analysis of Hela cells, using CDCA5 Antibody.

Purification:

Affinity-chromatography

Specificity:

CDCA5 Antibody detects endogenous levels of total CDCA5

Immunogen:

A synthesized peptide derived from human CDCA5

Description:

Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPAL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.