Alternative Names:

Apoptosis inducer NBK; Bcl-2 interacting killer; BIKLK; BIP1; BP4; NBK

Application:

WB IHC

Reactivity:

Human

Dilution:

WB 1:500-1:2000 IHC 1:50-1:200

	Western blot analysis of BIK phosphorylation expression in HepG2 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

Purification:

Affinity-chromatography

Specificity:

Phospho-BIK (Thr33) Antibody detects endogenous levels of BIK only when phosphorylated at Threonine 33

Immunogen:

A synthesized peptide derived from human BIK around the phosphorylation site of Threonine 33

Description:

The protein encoded by this gene is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.