Alternative Names:

CDC25M1, Dual specificity phosphatase Cdc25C, EC 3.1.3.48, M-phase inducer phosphatase 3, MPIP3

Application:

WB IHC

Reactivity:

Human

Dilution:

WB 1:500-1:2000 IHC 1:50-1:200

	Western blot analysis of CDC25C phosphorylation expression in serum treated HuvEc whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

Purification:

Affinity-chromatography

Specificity:

Phospho-CDC25C (Ser216) Antibody detects endogenous levels of CDC25C only when phosphorylated at Serine 216

Immunogen:

A synthesized peptide derived from human CDC25C around the phosphorylation site of Serine 216

Description:

a member of the MPI phosphatase family. Activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. Shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.