Alternative Names:

EC 2.7.11.24; ERK-1; ERK1; ERT2; Extracellular signal- regulated kinase 1; Insulin-stimulated MAP2 kinase; kinase ERK1; MAP kinase 1; MAPK 1; MAPK3; Microtubule- associated protein-2 kinase; Mitogen-activated protein kinase 3; MK03; MNK1; p44-ERK1; P44-ER

Application:

WB

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500-1:2000

	Western blot analysis of p44/42 MAP Kinase phosphorylation expression in EGF treated A431 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

Purification:

Affinity-chromatography

Specificity:

Phospho-p44/42 MAP Kinase (Thr202) Antibody detects endogenous levels of p44/42 MAP Kinase only when phosphorylated at Threonine 202

Immunogen:

A synthesized peptide derived from human p44/42 MAP Kinase around the phosphorylation site of Threonine 202

Description:

p42 MAP kinase plays a critical role in the regulation of cell growth and differentiation. Activated by a wide variety of extracellular signals including growth and neurotrophic factors, cytokines, hormones and neurotransmitters.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.