Alternative Names:

DIAPH1; DFNA1; DIA1; DIAP1; DIAPH1; DRF1; hDIA1; LFHL1;

Application:

WB IHC ICC/IF

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

	Western blot analysis of DIAPH1 expression in K562 cell lysate.

Purification:

Affinity-chromatography

Specificity:

DIAPH1 Antibody detects endogenous levels of total DIAPH1

Immunogen:

A synthesized peptide derived from human DIAPH1

Description:

Acts in a Rho-dependent manner to recruit PFY1 to the membrane. Required for the assembly of F-actin structures, such as actin cables and stress fibers. Nucleates actin filaments. Binds to the barbed end of the actin filament and slows down actin polymerization and depolymerization. Required for cytokinesis, and transcriptional activation of the serum response factor.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.