Alternative Names:

ESP2; HED2; ZYX; Zyxin2;

Application:

WB IHC ICC/IF IP FC

Reactivity:

Human Mouse

Dilution:

WB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:500

	Western blot analysis of Zyxin expression in MCF7 cell lysate.

Purification:

Affinity-chromatography

Specificity:

Zyxin Antibody detects endogenous levels of total Zyxin

Immunogen:

A synthesized peptide derived from human Zyxin

Description:

Zyxin binds alpha-actinin and the CRP proteins and is implicated in the regulation and modulation of actin filaments organization, cell adhesion, cell motility, mitosis, and signal transduction. Zyxin may shuttle between focal adhesion plaques and the nucleus. It has been suggested that zyxin is involved in gene transcription by its association with transcription factors in the nucleus.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.