Alternative Names:

JARID1A; Kdm5a; RBBP2; RBP2;

Application:

WB ICC/IF IP FC

Reactivity:

Human Mouse

Dilution:

WB 1:500~1:2000 ICC/IF 1:100~1:500 IP 1:80 FC 1:200

	Western blot analysis of KDM5A / Jarid1A / RBBP2 expression in (1) HEK293 cell lysate; (2) Mouse spleen lysate.

Purification:

Affinity-chromatography

Specificity:

KDM5A / Jarid1A / RBBP2 Antibody detects endogenous levels of total KDM5A / Jarid1A / RBBP2

Immunogen:

A synthesized peptide derived from human KDM5A / Jarid1A / RBBP2

Description:

Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.