Alternative Names:

ARF; CDK4I; CDKN2; CDKN2A; CMM2; INK4; INK4a; MLM; MTS1; p14; p16; p16INK4a; P19ARF; TP16;

Application:

WB ICC/IF IP FC

Reactivity:

Human

Dilution:

WB 1:500~1:1000 ICC/IF 1:50~1:200 IP 1:50 FC 1:80

	Western blot analysis of CDKN2A/p14ARF expression in PC3 cell lysate.

Purification:

Affinity-chromatography

Specificity:

CDKN2A/p14ARF Antibody detects endogenous levels of total CDKN2A/p14ARF

Immunogen:

A synthesized peptide derived from human CDKN2A/p14ARF

Description:

The gene for CDK2NA generates several transcripts/proteins which differ from each other in their first exons. Three of these transcripts are generated by alternative splicing (isoform 1 a.k.a p16INK4A, isoform 2 and isoform 3 a.k.a p12), two of which are known to function as inhibitors of CDK4 kinase.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.