Alternative Names:

NBLST2; NBPhox; PHOX 2B; PHOX2B; PMX 2B; PMX2B;

Application:

WB IHC ICC/IF

Reactivity:

Human Mouse

Dilution:

WB 1:500~1:2000 IHC 1:100~1:500 ICC/IF 1:50~1:200

	Western blot analysis of PHOX2B expression in Neuro-2a cell lysate.

Purification:

Affinity-chromatography

Specificity:

PHOX2B Antibody detects endogenous levels of total PHOX2B

Immunogen:

A synthesized peptide derived from human PHOX2B

Description:

Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.