Alternative Names:

ALC1; chd1l; CHDL;

Application:

WB IHC ICC/IF IP FC

Reactivity:

Human Mouse

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:40 FC 1:200

	Western blot analysis of CHD1L expression in A549 cell lysate.

Purification:

Affinity-chromatography

Specificity:

CHD1L Antibody detects endogenous levels of total CHD1L

Immunogen:

A synthesized peptide derived from human CHD1L

Description:

DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.