Alternative Names:

p70 alpha; P70 beta 1; p70 S6K; P70S6K; P70S6K1; p70S6Kb; PS6K; RPS6KB1; S6K; S6K1; STK14A;

Application:

WB IHC ICC/IF FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:1000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:200

	Western blot analysis of P70 S6 Kinase alpha expression in (1) HeLa cell lysate; (2) Raw264.7 cell lysate; (3) PC12 cell lysate.

Purification:

Affinity-chromatography

Specificity:

P70 S6 Kinase alpha Antibody detects endogenous levels of total P70 S6 Kinase alpha

Immunogen:

A synthesized peptide derived from human P70 S6 Kinase alpha

Description:

Acts to integrate nutrient and growth factor signals in regulation of protein synthesis, cell proliferation, cell growth, cell cycle progression and cell survival. Downstream effector of the mTOR signaling pathway.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.