Alternative Names:

COREST; Nr2b2; RCOR; Rcor1; Rxrb;

Application:

WB IHC ICC/IF

Reactivity:

Human Mouse Rat

Dilution:

WB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:50~1:200

	Western blot analysis of CoREST expression in Molt-4 cell lysate.

Purification:

Affinity-chromatography

Specificity:

CoREST Antibody detects endogenous levels of total CoREST

Immunogen:

A synthesized peptide derived from human CoREST

Description:

Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.