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IL1R2 Polyclonal Antibody
IL1RB, CD121b, CDw121b, IL-1R-2, IL-1RT2, IL-1RT-2
货号:YBAP10225 |
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规格: 50ul/100ul/200ul |
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价格: 980/1280/1890 |
Immunogen: | Recombinant protein of human IL1R2 | ||
Synonym: |
IL1RB, CD121b, CDw121b, IL-1R-2, IL-1RT2, IL-1RT-2 | ||
Calculated MW: | |||
Observed MW: | |||
Source: |
Rabbit |
Isotype: |
IgG | ||
Application: |
ELISA IHC | ||
Purify: |
Affinity purification | ||
Concentration: |
0.61mg/ml | ||
Storage Buffer: |
PBS with 0.05% sodium azide, 50% glycerol, pH7.3 | ||
Storage: |
Store at -20℃. Avoid freeze / thaw cycles. |
Immunohistochemistry of Human lung cancer using IL1R2 Polyclonal Antibody at dilution of 1:20 |
Protocols: |
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide |
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Background: |
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage.
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