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DTX2 Polyclonal Antibody
RNF58
货号:YBAP10413
价格: 980/1280/1890
Immunogen: Recombinant protein of human DTX2
Synonym:
RNF58
Calculated MW:
Observed MW:
Source:
Rabbit
Isotype:
IgG
Reactivity: H,M;

Clonality: Polyclonal


Application:
ELISA IHC
Purify:
Affinity purification
Concentration:
0.6mg/ml
Storage Buffer:
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
DTX2 Polyclonal Antibody


Immunohistochemistry of Human thyroid cancer using DTX2 Polyclonal Antibody at dilution of 1:15

Protocols:
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide
Background:
DTX2 functions as an E3 ubiquitin ligase. Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

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